View abstract. 2010;26(6):623-626. WebLutein is a nutrient best known for its help maintaining eye health, though it may have other health benefits as well. Keep in mind that as with other antioxidants, people seem to differ in terms of how capable their bodies are of absorbing lutein. J.Matern.Fetal Neonatal Med. Likely not, but overall we still have a way to go when it comes to understanding the full potential of lutein in terms of disease prevention, bioavailability, metabolism and dose-response relationships. Spraycar M, ed. View abstract. It's related to beta-carotene and vitamin A. Lutein-rich foods include egg yolks, broccoli, spinach, kale, corn, orange pepper, kiwi fruit, grapes, orange juice, zucchini and squash. A multicenter randomized controlled study of antioxidant supplementation with lutein for chronic central serous chorioretinopathy. Nutrition 2012;28(6):605-610. It is certified by the National Eczema Association, meaning it is safe for those with eczema or sensitive skina testament to its mildness. Am J Respir Crit Care Med 2001;163:1246-55.. View abstract. Adackapara, C. A., Sunness, J. S., Dibernardo, C. W., Melia, B. M., and Dagnelie, G. Prevalence of cystoid macular edema and stability in oct retinal thickness in eyes with retinitis pigmentosa during a 48-week lutein trial. Montonen J, Knekt P, Jarvinen R, Reunanen A. Dietary antioxidant intake and risk of type 2 diabetes. Nutr Res 2001;21:797-809. 1997;6(8):617-623. 2012;22(2):216-225. Sasamoto, Y., Gomi, F., Sawa, M., Tsujikawa, M., and Nishida, K. Effect of 1-year lutein supplementation on macular pigment optical density and visual function. Castenmiller, J. J., Lauridsen, S. T., Dragsted, L. O., het Hof, K. H., Linssen, J. P., and West, C. E. beta-carotene does not change markers of enzymatic and nonenzymatic antioxidant activity in human blood. Exp.Gerontol. Dwyer, J. H., Navab, M., Dwyer, K. M., Hassan, K., Sun, P., Shircore, A., Hama-Levy, S., Hough, G., Wang, X., Drake, T., Merz, C. N., and Fogelman, A. M. Oxygenated carotenoid lutein and progression of early atherosclerosis: the Los Angeles atherosclerosis study. View abstract. Br J Nutr 2004;92(1):113-118. View abstract. Aune, D., Chan, D. S., Vieira, A. R., Navarro Rosenblatt, D. A., Vieira, R., Greenwood, D. C., and Norat, T. Dietary compared with blood concentrations of carotenoids and breast cancer risk: a systematic review and meta-analysis of prospective studies. View abstract. Arch.Biochem.Biophys. Neuroepidemiology. Am.J.Clin.Nutr. Djuric, Z., Uhley, V. E., Naegeli, L., Lababidi, S., Macha, S., and Heilbrun, L. K. Plasma carotenoids, tocopherols, and antioxidant capacity in a 12-week intervention study to reduce fat and/or energy intakes. Photochem.Photobiol. View abstract. Nutr Neurosci 2008;11(2):75-83. That is exactly why the lens needs to remain clear and free from the cloudiness that is indicative of cataracts. View abstract. 2003;16(8):665-672. A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa. Cui YH, Jing CX, Pan HW. 2004;3(6):310-316. Prospective study of lutein/zeaxanthin intake and risk of age-related macular degeneration. 1995;36(12):2531-2541. A., Hollenbach, K. A., Newman, V. A., Faerber, S., Ritenbaugh, C. K., Gold, E., Stefanick, M. L., Jones, L. A., Marshall, J. R., and Pierce, J. P. On the importance of using multiple methods of dietary assessment. 2003;42(6):315-323. Giordano, P., Scicchitano, P., Locorotondo, M., Mandurino, C., Ricci, G., Carbonara, S., Gesualdo, M., Zito, A., Dachille, A., Caputo, P., Riccardi, R., Frasso, G., Lassandro, G., Di, Mauro A., and Ciccone, M. M. Carotenoids and cardiovascular risk. 2014 May;174(5):763-71. Dietary lutein and cognitive function in adults: A meta-analysis of randomized controlled trials. At this time there isnt a general recommendation for daily intake of lutein or zeaxanthin. Some might have a harder time utilizing it and other antioxidants from foods and transporting to tissues within the eyes or other organs. Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial. View abstract. View abstract. Malila, N., Virtamo, J., Virtanen, M., Pietinen, P., Albanes, D., and Teppo, L. Dietary and serum alpha-tocopherol, beta-carotene and retinol, and risk for colorectal cancer in male smokers. Association of blood antioxidants and vitamins with risk of age-related cataract: a meta-analysis of observational studies. Lutein is best absorbed when taken with a View abstract. View abstract. Age-Related Eye Disease Study 2 Research Group. View abstract. Maternal lutein and zeaxanthin concentrations in relation to offspring visual acuity at 3 years of age: The GUSTO Study. View abstract. View abstract. 2006;82(5):915-920. View abstract. Carcinogenesis 1997;18(9):1847-1850. Am J Epidemiol 1999;149:801-9. View abstract. View abstract. Rapp, L. M., Maple, S. S., and Choi, J. H. Lutein and zeaxanthin concentrations in rod outer segment membranes from perifoveal and peripheral human retina. Bowen, P. E., Herbst-Espinosa, S. M., Hussain, E. A., and Stacewicz-Sapuntzakis, M. Esterification does not impair lutein bioavailability in humans. Richer S, Stiles W, Statkute L, et al. BMJ 1992;305:335-9. Association between dietary carotenoid intakes and the risk of asthma in adults: a cross-sectional study of NHANES, 2007-2012. Creatine therapy in myophosphorylase deficiency (McArdle disease): a placebo-controlled crossover trial. Am J Clin Nutr 1995;62:1448S-61S.. View abstract. Prog Retin Eye Res. 2012;90(5):e399-e403. are clickable links to medically peer-reviewed studies. View abstract. Mahmassani HA, Switkowski KM, Johnson EJ, et al. Fruits and vegetables that are sources for lutein and zeaxanthin: the macular pigment in human eyes. 2009;41(9):1752-1760. Carotenoids are a group of naturally occurring pigments that are largely responsible for the red, yellow, and orange color of fruits and vegetables and some animals. Zhou Y, Wang T, Meng Q, Zhai S. Association of carotenoids with risk of gastric cancer: a meta-analysis. WebLutein & Zeaxanthin Eye Health Supplement for Adults - Delicious Vegan Eye Vitamins Lutein and Zeaxanthin Gummies - Zeaxanthin Plus Lutein 20mg for Vision Clarity Dry Eye Relief and Blue Light Support. 2012;53(12):7871-7880. The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Invest Ophthalmol.Vis.Sci. View abstract. View abstract. O'Neill, M. E., Carroll, Y., Corridan, B., Olmedilla, B., Granado, F., Blanco, I., van den, Berg H., Hininger, I., Rousell, A. M., Chopra, M., Southon, S., and Thurnham, D. I. 1996;36(13):2001-2012. Luckily, doctors now have the ability to measure macular pigment levels of lutein in someones eyes in order to determine if that person is at an increased risk for disease. View abstract. Am.J Clin.Nutr 1996;64(4):594-602. Ophthalmology 2003;110(1):51-60. Mol.Nutr.Food Res. JAMA. View abstract. Studies done by the University of Southern California suggest that low levels of lutein within the blood might contribute to the thickening of artery walls. Bone, R. A., Landrum, J. T., Mayne, S. T., Gomez, C. M., Tibor, S. E., and Twaroska, E. E. Macular pigment in donor eyes with and without AMD: a case-control study. View abstract. View abstract. Eye Disease Case-Control Study Group. View abstract. View abstract. View abstract. Invest Ophthalmol.Vis.Sci. 2012;53(10):6178-6186. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Shao, A. and Hathcock, J. N. Risk assessment for the carotenoids lutein and lycopene. View abstract. Iribarren, C., Folsom, A. R., Jacobs, D. R., Jr., Gross, M. D., Belcher, J. D., and Eckfeldt, J. H. Association of serum vitamin levels, LDL susceptibility to oxidation, and autoantibodies against MDA-LDL with carotid atherosclerosis. View abstract. 2000;46(11):1818-1829. Olestra affects serum concentrations of alpha-tocopherol and carotenoids but not vitamin D or vitamin K status in free-living subjects. Cancer Epidemiol.Biomarkers Prev. 2012;107(3):350-359. The pharmacological effects of quercetin, such as its antioxidant, anti-inflammatory, antiallergic, antiaging, and anticancer activities, as well as its regulating effect on interleukin (IL)-6, IL-8, tumor necrosis factor (TNF), histamine, and tryptase release in mast cells, are well acknowledged [9]. However, most studies show that benefits are greatest when someone consumes 10 milligrams of lutein per day or more (along with about two milligrams of zeaxanthin perday). Brown L, Rimm EB, Seddon JM, et al. A., Snodderly, D. M., Klein, M. L., Wooten, B. R., and Chappell, R. Macular pigment density and age-related maculopathy in the Carotenoids in Age-Related Eye Disease Study. Appl.Ergon. J Nutr 1999;129(12):2162-2169. 2012;56(2):270-286. Dietary intake of antioxidants and risk of age-related macular degeneration. Invest Ophthalmol.Vis.Sci. View abstract. Optom Vis Sci 1997;74:499-504. Chew EY, SanGiovanni JP, Ferris FL, et al. Foods Zinc. Front Aging Neurosci 2017;9:254. Lutein, zeaxanthin, and meso-zeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease. Hammond BR Jr, Wooten BR, Snodderly DM, et al. Am J Clin Nutr 2005;82(3):685-693. 2013;54(3):1781-1788. Cancer Causes Control 1997;8:575-90. Ophthalmic Res. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), Wet Age-Related Macular Degeneration and Vision Loss, An eye disease that leads to vision loss in older adults (age-related macular degeneration or AMD). JAMA Intern Med. Am.J.Ophthalmol. Invest Ophthalmol Vis Sci 1995;36:276-88. Am.J.Epidemiol. Nutrient intake and cataract extraction in women: a prospective study. J Nutr 2021;151(3):615-627. Tan, J. S., Wang, J. J., Flood, V., Rochtchina, E., Smith, W., and Mitchell, P. Dietary antioxidants and the long-term incidence of age-related macular degeneration: the Blue Mountains Eye Study. View abstract. View abstract. A. View abstract. View abstract. 2001;42(2):439-446. Ophthalmology 2002;109:2272-8.. View abstract. Xu X, Zhao X, Berde Y, Low YL, Kuchan MJ. Am J Clin Nutr 2004;80:1508-20. Nutrients 2016;8(7). Am J Clin Nutr 2003;78(5):985-992. Slattery ML, Benson J, Curtin K, et al. Teikari JM, Virtamo J, Rautalahti M, et al. 1996;66(4):316-321. 2002;75(5):503-506. The ARIC Study Investigators. To preserve skin health and fight skin cancer, lutein helps filter high-energy wavelengths of visible light, which slows down the rate of oxidative stress. View abstract. Natarajan, L., Rock, C. L., Major, J. M., Thomson, C. A., Caan, B. J., Flatt, S. W., Chilton, J. Incidence of cataract operations in Finnish male smokers unaffected by alpha tocopherol or beta carotene supplements. It occurs in certain algae and causes the pink-red color in salmon. View abstract. J Nutr 2002;132:3668-73. 80 mg of zinc. Zhang PC, Wu CR, Wang ZL, Wang LY, Han Y, Sun SL, et al. Murray, I. J., Makridaki, M., van der Veen, R. L., Carden, D., Parry, N. R., and Berendschot, T. T. Lutein supplementation over a one-year period in early AMD might have a mild beneficial effect on visual acuity: the CLEAR study. View abstract. Curr.Eye Res. Cancer Causes Control 2003;14(7):645-655. Snodderly DM. View abstract. 2005;15 Suppl 2:S140-S149. Ma, L., Dou, H. L., Huang, Y. M., Lu, X. R., Xu, X. R., Qian, F., Zou, Z. Y., Pang, H. L., Dong, P. C., Xiao, X., Wang, X., Sun, T. T., and Lin, X. M. Improvement of retinal function in early age-related macular degeneration after lutein and zeaxanthin supplementation: a randomized, double-masked, placebo-controlled trial. Previous studies have found that lutein helps bolster the skins natural antioxidant system and protect against sun damage, and reduces the risk of age-related Effect of beta-carotene supplementation and lactation on carotenoid metabolism and mitogenic T-lymphocyte proliferation. Parisi V, Tedeschi M, Gallinaro G, et al. View abstract. Br.J Nutr 1999;82(3):203-212. View abstract. View abstract. View abstract. Cardinault, N., Tyssandier, V., Grolier, P., Winklhofer-Roob, B. M., Ribalta, J., Bouteloup-Demange, C., Rock, E., and Borel, P. Comparison of the postprandial chylomicron carotenoid responses in young and older subjects. Zeaxanthin, and meso-zeaxanthin: the basic and Clinical science underlying carotenoid-based nutritional interventions against ocular disease randomized. 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